Review



optimal compartment model  (MicroMath Inc)

 
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    MicroMath Inc optimal compartment model
    Radioactivity concentrations, parent radioligand fraction in plasma, and brain time activity curves from a representative subject injected with [11C]FPEB (a–c) or [11C]SP203 (d–f). The first panels (a and d) for each radioligand plot the concentration of parent radioligand, separated from radiometabolites as a function of time after injection. The middle panels (b and e) show the percentage of total radioactivity in plasma that represents parent radioligand. The last panels (c and f) plot the concentrations of radioactivity in three brain regions as a function of time after injection. The lines represent the unconstrained two-tissue <t>compartment</t> model that well fit all data points. (o) putamen, (•) thalamus, and (□) cerebellum.
    Optimal Compartment Model, supplied by MicroMath Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/optimal+compartment+model/pmc05531344-256-2-25?v=MicroMath+Inc
    Average 90 stars, based on 1 article reviews
    optimal compartment model - by Bioz Stars, 2026-06
    90/100 stars

    Images

    1) Product Images from "Comparison of two PET radioligands, [ 11 C]FPEB and [ 11 C]SP203, for quantification of metabotropic glutamate receptor 5 in human brain"

    Article Title: Comparison of two PET radioligands, [ 11 C]FPEB and [ 11 C]SP203, for quantification of metabotropic glutamate receptor 5 in human brain

    Journal: Journal of Cerebral Blood Flow & Metabolism

    doi: 10.1177/0271678X16668891

    Radioactivity concentrations, parent radioligand fraction in plasma, and brain time activity curves from a representative subject injected with [11C]FPEB (a–c) or [11C]SP203 (d–f). The first panels (a and d) for each radioligand plot the concentration of parent radioligand, separated from radiometabolites as a function of time after injection. The middle panels (b and e) show the percentage of total radioactivity in plasma that represents parent radioligand. The last panels (c and f) plot the concentrations of radioactivity in three brain regions as a function of time after injection. The lines represent the unconstrained two-tissue compartment model that well fit all data points. (o) putamen, (•) thalamus, and (□) cerebellum.
    Figure Legend Snippet: Radioactivity concentrations, parent radioligand fraction in plasma, and brain time activity curves from a representative subject injected with [11C]FPEB (a–c) or [11C]SP203 (d–f). The first panels (a and d) for each radioligand plot the concentration of parent radioligand, separated from radiometabolites as a function of time after injection. The middle panels (b and e) show the percentage of total radioactivity in plasma that represents parent radioligand. The last panels (c and f) plot the concentrations of radioactivity in three brain regions as a function of time after injection. The lines represent the unconstrained two-tissue compartment model that well fit all data points. (o) putamen, (•) thalamus, and (□) cerebellum.

    Techniques Used: Radioactivity, Clinical Proteomics, Activity Assay, Injection, Concentration Assay

    Distribution volume (VT) as a function of duration of image acquisition for [11C]FPEB (a) and [11C]SP203 (b). VT was calculated for cerebellum (•) using an unconstrained two-tissue compartment model with increasingly truncated acquisition times. Values are normalized as percentage of terminal value attained from 120 min of imaging. Data represent mean ± SD of eight subjects for [11C]FPEB and six subjects for [11C]SP203.
    Figure Legend Snippet: Distribution volume (VT) as a function of duration of image acquisition for [11C]FPEB (a) and [11C]SP203 (b). VT was calculated for cerebellum (•) using an unconstrained two-tissue compartment model with increasingly truncated acquisition times. Values are normalized as percentage of terminal value attained from 120 min of imaging. Data represent mean ± SD of eight subjects for [11C]FPEB and six subjects for [11C]SP203.

    Techniques Used: Imaging



    Similar Products

    optimal compartment model  (MicroMath Inc)
    90
    MicroMath Inc optimal compartment model
    Radioactivity concentrations, parent radioligand fraction in plasma, and brain time activity curves from a representative subject injected with [11C]FPEB (a–c) or [11C]SP203 (d–f). The first panels (a and d) for each radioligand plot the concentration of parent radioligand, separated from radiometabolites as a function of time after injection. The middle panels (b and e) show the percentage of total radioactivity in plasma that represents parent radioligand. The last panels (c and f) plot the concentrations of radioactivity in three brain regions as a function of time after injection. The lines represent the unconstrained two-tissue <t>compartment</t> model that well fit all data points. (o) putamen, (•) thalamus, and (□) cerebellum.
    Optimal Compartment Model, supplied by MicroMath Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/optimal+compartment+model/pmc05531344-256-2-25?v=MicroMath+Inc
    Average 90 stars, based on 1 article reviews
    optimal compartment model - by Bioz Stars, 2026-06
    90/100 stars
    		  Buy from Supplier
    compartment model  (MathWorks Inc)
    96
    MathWorks Inc compartment model
    Radioactivity concentrations, parent radioligand fraction in plasma, and brain time activity curves from a representative subject injected with [11C]FPEB (a–c) or [11C]SP203 (d–f). The first panels (a and d) for each radioligand plot the concentration of parent radioligand, separated from radiometabolites as a function of time after injection. The middle panels (b and e) show the percentage of total radioactivity in plasma that represents parent radioligand. The last panels (c and f) plot the concentrations of radioactivity in three brain regions as a function of time after injection. The lines represent the unconstrained two-tissue <t>compartment</t> model that well fit all data points. (o) putamen, (•) thalamus, and (□) cerebellum.
    Compartment Model, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/optimal+compartment+model/pm16894991-220-19-32?v=MathWorks+Inc
    Average 96 stars, based on 1 article reviews
    compartment model - by Bioz Stars, 2026-06
    96/100 stars
    		  Buy from Supplier
    optimal impulsive control of compartment models, ii: algorithm  (Thermo Fisher)
    90
    Thermo Fisher optimal impulsive control of compartment models, ii: algorithm
    Radioactivity concentrations, parent radioligand fraction in plasma, and brain time activity curves from a representative subject injected with [11C]FPEB (a–c) or [11C]SP203 (d–f). The first panels (a and d) for each radioligand plot the concentration of parent radioligand, separated from radiometabolites as a function of time after injection. The middle panels (b and e) show the percentage of total radioactivity in plasma that represents parent radioligand. The last panels (c and f) plot the concentrations of radioactivity in three brain regions as a function of time after injection. The lines represent the unconstrained two-tissue <t>compartment</t> model that well fit all data points. (o) putamen, (•) thalamus, and (□) cerebellum.
    Optimal Impulsive Control Of Compartment Models, Ii: Algorithm, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/optimal+compartment+model/10__1115_slash_1__3426439-362-4-10?v=Thermo+Fisher
    Average 90 stars, based on 1 article reviews
    optimal impulsive control of compartment models, ii: algorithm - by Bioz Stars, 2026-06
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Radioactivity concentrations, parent radioligand fraction in plasma, and brain time activity curves from a representative subject injected with [11C]FPEB (a–c) or [11C]SP203 (d–f). The first panels (a and d) for each radioligand plot the concentration of parent radioligand, separated from radiometabolites as a function of time after injection. The middle panels (b and e) show the percentage of total radioactivity in plasma that represents parent radioligand. The last panels (c and f) plot the concentrations of radioactivity in three brain regions as a function of time after injection. The lines represent the unconstrained two-tissue compartment model that well fit all data points. (o) putamen, (•) thalamus, and (□) cerebellum.

    Journal: Journal of Cerebral Blood Flow & Metabolism

    Article Title: Comparison of two PET radioligands, [ 11 C]FPEB and [ 11 C]SP203, for quantification of metabotropic glutamate receptor 5 in human brain

    doi: 10.1177/0271678X16668891

    Figure Lengend Snippet: Radioactivity concentrations, parent radioligand fraction in plasma, and brain time activity curves from a representative subject injected with [11C]FPEB (a–c) or [11C]SP203 (d–f). The first panels (a and d) for each radioligand plot the concentration of parent radioligand, separated from radiometabolites as a function of time after injection. The middle panels (b and e) show the percentage of total radioactivity in plasma that represents parent radioligand. The last panels (c and f) plot the concentrations of radioactivity in three brain regions as a function of time after injection. The lines represent the unconstrained two-tissue compartment model that well fit all data points. (o) putamen, (•) thalamus, and (□) cerebellum.

    Article Snippet: The optimal compartment model (i.e. one- vs. two-tissue compartment) was chosen based on the Akaike information criterion (AIC), 18 model selection criterion (MSC) proposed by Micromath®, Saint Louis, MO, http://www.micromath.com/products.php?p=scientist&m=statistical_analysis ), and F -test.

    Techniques: Radioactivity, Clinical Proteomics, Activity Assay, Injection, Concentration Assay

    Distribution volume (VT) as a function of duration of image acquisition for [11C]FPEB (a) and [11C]SP203 (b). VT was calculated for cerebellum (•) using an unconstrained two-tissue compartment model with increasingly truncated acquisition times. Values are normalized as percentage of terminal value attained from 120 min of imaging. Data represent mean ± SD of eight subjects for [11C]FPEB and six subjects for [11C]SP203.

    Journal: Journal of Cerebral Blood Flow & Metabolism

    Article Title: Comparison of two PET radioligands, [ 11 C]FPEB and [ 11 C]SP203, for quantification of metabotropic glutamate receptor 5 in human brain

    doi: 10.1177/0271678X16668891

    Figure Lengend Snippet: Distribution volume (VT) as a function of duration of image acquisition for [11C]FPEB (a) and [11C]SP203 (b). VT was calculated for cerebellum (•) using an unconstrained two-tissue compartment model with increasingly truncated acquisition times. Values are normalized as percentage of terminal value attained from 120 min of imaging. Data represent mean ± SD of eight subjects for [11C]FPEB and six subjects for [11C]SP203.

    Article Snippet: The optimal compartment model (i.e. one- vs. two-tissue compartment) was chosen based on the Akaike information criterion (AIC), 18 model selection criterion (MSC) proposed by Micromath®, Saint Louis, MO, http://www.micromath.com/products.php?p=scientist&m=statistical_analysis ), and F -test.

    Techniques: Imaging